职称：讲师
所在部门：计算机科学与工程系
办公地点：信息科技大楼404
孟巧珍，博士，讲师。2024年6月毕业于天津大学智能与计算学部计算机应用技术专业，获工学博士学位。目前在湘潭大学计算机学院工作。研究方向为机器学习、深度学习、生物信息学等，主要从事人工智能算法助力蛋白质及多肽序列、结构与功能发现、酶优化改造、从头设计以及功能预测等。近年来在NeurIPS、AAAI、Briefings in Bioinformatics、IEEE/ACM Transactions on Computational Biology and Bioinformatics等多个重要期刊和会议上发表论文10余篇。主持/参与科技部重点研发项目、国家自然科学基金（面上、青年）项目、湖南省自然科学青年基金等项目。担任BIBM、ICLR、BMC Bioinformatics等会议和期刊审稿人。
团队常年招收硕士研究生和本科生，欢迎有兴趣生物信息学的同学加入，请与我邮件联系！团队长期与国内外高水平科研单位（中南大学、中科院深圳先进院等）保持长期稳定合作关系。
工作经历
2024-至今 湘潭大学 计算机学院
研究领域
1. 机器学习、深度学习
2. 生物信息学
代表作
2024以来：
1. Diya Zhang, Mengwei Sun, Xingdan Wang, Cheng Liang*, Qiaozhen Meng*, Shiqiang Ma*, Fei Guo*, “DynaPhArM: Adaptive and Physics-Constrained Modeling for Target-Drug Complexes with Drug-Specific Adaptations,” In Proceedings of the Thirty-ninth Annual Conference on Neural Information Processing Systems (NeurIPS), San Diego, United States & Mexico City, Mexico, 2025. 【国际人工智能三大顶会之一，CCF推荐A类国际会议】
2. Chengwei AI, Qiaozhen Meng, Mengwei Sun, Ruihan Dong, Hongpeng Yang, Shiqiang Ma*, Xiaoyi Liu*, Cheng Liang*, Fei Guo*, “PharmaQA: Prompt-Based Molecular Representation Learning via Pharmacophore-Oriented Question Answering,” In Proceedings of the AAAI Conference on Artificial Intelligence (AAAI), Philadelphia, USA, 2025. 【CCF推荐A类国际会议】
3. Mengwei Sun, Chengwei Ai, Diya Zhang, Xiaoyi Liu, Qiaozhen Meng*, Shiqiang Ma*, Fei Guo*, “MolInterAct:Multiscale Cross-modal Interaction for Robust Molecular Representation Learning,” In IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2024. 【CCF B类会议】
4. Xingdan Wang, Diya Zhang, Chengwei Ai, Shiqiang Ma*, Qiaozhen Meng*, Junwen Duan*, Fei Guo*, “MultiPepDec: Decoupled Prompt Learning for Multi-Activity Therapeutic Peptides,” In IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2024. 【CCF B类会议】
5. Qiaozhen Meng, Genlang Chen, Bin Lin, Shixin Zheng, Yulai Lin, Jijun Tang*, Fei Guo*. DMAMP: A Deep-Learning Model for Detecting Antimicrobial Peptides and Their Multi-Activities [J]. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2024. 【CCF B 推荐期刊】
6. Qiaozhen Meng, Yinuo Lyu, Xiaoqing Peng, Junhai Xu, Jijun Tang*, Fei Guo*. EPIMR: Prediction of enhancer-promoter interactions by multi-scale ResNet on image representation [J]. Big Data Mining and Analytics, 2024, 7(3): 668-681. 【中科院一区, IF: 13.6】
7. Jia Jin+, Qiaozhen Meng+, Guihua Duan*, Ercheng Wang*, Fei Guo*. Rapid screening of multi-point mutations for enzyme thermostability modification by utilizing computational tools [J]. Future Generation Computer Systems, 2024, 160: 724-738. 【共一，中科院一区Top期刊, IF: 13.6】
8. Beibei Zhang+, Qiaozhen Meng+, Chengwei Ai, Guihua Duan, Ercheng Wang*, Fei Guo*. Comparative Analysis of Deep Generative Model for Industrial Enzyme Design [J]. Current Bioinformatics, 2024.【共一，JCR 1区】
2021-2023年：
1. Qiaozhen Meng, Fei Guo*, Jijun Tang*. Improved structure-related prediction for insufficient homologous proteins using MSA enhancement and pre-trained language model [J]. Briefings in Bioinformatics, 2023, 24(4): 1-14. 【中科院一区, 生物信息领域Top 期刊】
2. Qiaozhen Meng, Jijun Tang, Fei Guo*, “Multi-AMP: detecting the antimicrobial peptides and their activities using the multi-task learning,” In IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2021. 【CCF B类会议】
3. Qiaozhen Meng, Fei Guo*, Ercheng Wang *, Jijun Tang*. ComDock: A novel approach for protein-protein docking with an efficient fusing strategy [J]. Computers in Biology and Medicine, 2023, 167:107660.【Top 期刊】
4. Wei Zhang+, Qiaozhen Meng+, Jianxin Wang, Fei Guo*. HDIContact: a novel predictor of residue-residue contacts on hetero-dimer interfaces via sequential information and transfer learning strategy [J]. Briefings in Bioinformatics, 2022, 23(4): bbac169.【共一, 生物信息领域Top 期刊】
5. Wei Zhang+, Qiaozhen Meng+, Jijun Tang, Fei Guo*. Exploring effectiveness of ab-initio protein-protein docking methods on a novel antibacterial protein complex dataset [J]. Briefings in Bioinformatics, 2021, 22(6): bbab150. 【共一, 生物信息领域Top 期刊】
科研项目
1. 湖南省自然科学基金青年项目，多肽药物的智能识别及从头设计方法研究，2025JJ60387，2025/01-2027/12，主持.
主讲课程
1. 《数学分析Ⅱ 1》、《数学分析Ⅱ 2》
2. 《高级软件技术实践》
3. 《虚拟现实技术与应用》
社会兼职、获奖项目
1. CCF生物信息学专委会通讯委员；
2. 担任BIBM、BMC Bioinformatics期刊、ICLR等期刊和会议审稿人；
3. 湘潭大学计算机学院课程思政教学竞赛一等奖，2025.
